| 12:00 PM | █ North Carolina @ Georgia Tech | ESPN | Dave Pasch, Brian Griese |
| 12:00 PM | █ San Jose State @ Minnesota | ESPN2 | Beth Mowins, Joey Galloway |
| 12:00 PM | █ Louisiana Tech @ Kansas | FOX Sports 1 | Justin Kutcher, James Bates |
| 12:00 PM | █ Marshall @ Virginia Tech | ESPNU | Tom Hart, John Congemi |
| 12:00 PM | █ Vanderbilt @ Massachusetts | ESPNEWS | Dave Lamont, Ray Bentley |
| 12:00 PM | █ Florida A&M @ #4 Ohio State | BTN | Matt Devlin, Glen Mason |
| 12:00 PM | █ Western Michigan @ Iowa | BTN | Wayne Larrivee, Jon Jansen |
| 12:00 PM | █ Wake Forest @ Army | CBSSN | Ben Holden, Tom Bradley |
| 12:00 PM | █ North Texas @ #9 Georgia | SEC TV | Dave Neal, Andre Ware |
| 12:00 PM | █ Toledo @ Central Michigan | ESPN+ | Michael Reghi, Doug Graber |
| 12:00 PM | █ FIU @ #7 Louisville | WHAS 11 Louisville | Drew Deener, Doug James |
| 12:00 PM | █ Middle Tennessee @ FAU | CSS, CSN Hou, CSN Calif | Matt Stewart, Chuck Oliver |
| 12:30 PM | █ Pittsburgh @ Duke | ACC Network | Steve Martin, Dave Archer |
| 12:30 PM | █ Tulane @ Syracuse | FSN/CSN regional | Wes Durham, Brian Stann |
| 1:00 PM | █ Ball State @ Eastern Michigan | ESPN3 | Dan Gutowsky, Forrest Conoly |
| 2:00 PM | █ Austin Peay @ Ohio | ESPN3 | Keith Morehouse, Rocky Boiman |
| 2:00 PM | █ Jacksonville State @ Georgia State | ESPN3 | Roy Philpott, Peter Vaas |
| 3:00 PM | █ Idaho State @ #17 Washington | Pac-12 Network | Kevin Calabro, Yogi Roth |
| 3:00 PM | █ Houston vs Rice
(in Reliant Stadium) | FSN regional | Mark Followill, Brian Baldinger |
| 3:00 PM | █ Northwestern State @ UAB | | |
| 3:30 PM | █ Purdue @ #24 Wisconsin | ABC/ESPN2 | Mike Patrick, Ed Cunningham |
| 3:30 PM | █ Utah State @ USC | ABC/ESPN2 | Dave Flemming, David Diaz-Infante |
| 3:30 PM | █ Tennessee @ #19 Florida | CBS | Verne Lundquist, Gary Danielson |
| 3:30 PM | █ Michigan State @ #22 Notre Dame | NBC | Dan Hicks, Mike Mayock |
| 3:30 PM | █ Arkansas @ Rutgers | ESPN | Bob Wischusen, Rod Gilmore |
| 3:30 PM | █ West Virginia @ Maryland | ESPNU | Anish Shroff, Kelly Stouffer |
| 3:30 PM | █ Kent State @ Penn State | BTN | Kevin Kugler, Chuck Long |
| 3:30 PM | █ Maine @ #18 Northwestern | BTN | Josh Lewin, J. Leman |
| 3:30 PM | █ South Dakota State @ Nebraska | BTN | Paul Burmeister, Eric Crouch |
| 3:30 PM | █ Murray State @ Bowling Green | ESPN3 | Dave Weekley, John Gregory |
| 3:30 PM | █ VMI @ Virginia | ESPN3 | Shawn Kenney, Stan Lewter |
| 4:00 PM | █ ULM @ #20 Baylor | FOX Sports 1 | Craig Bolerjack, Joey Harrington |
| 4:00 PM | █ Cincinnati @ Miami (OH) | ESPN3 | Jim Barbar, Pete Najarian |
| 4:30 PM | █ Arkansas State @ Memphis | ESPN3 | Joel Meyers, Kevin O'Connell |
| 6:00 PM | █ ULL @ Akron | ESPN3 | Frank Giardina, Jerod Cherry |
| 6:00 PM | █ Bethune-Cookman @ #8 Florida State | ESPN3 | John Sadak, Al Groh |
| 7:00 PM | █ #23 Arizona State @ #5 Stanford | FOX | Gus Johnson, Charles Davis |
| 7:00 PM | █ Colorado State @ #1 Alabama | ESPN2 | Joe Tessitore, Matt Millen |
| 7:00 PM | █ Southern Methodist @ #10 Texas A&M | ESPNU | Clay Matvick, Matt Stinchcomb |
| 7:00 PM | █ Eastern Illinois @ Northern Illinois | ESPN3 | Mike Couzens, Bob Chmeil |
| 7:00 PM | █ Morgan State @ Western Kentucky | ESPN3 | Trey Bender, Brian Kinchen |
| 7:00 PM | █ Savannah State @ #16 Miami | ESPN3 | Drew Fellios, Cory Chavous |
| 7:00 PM | █ Texas State @ #25 Texas Tech | FSN regional, FCS Pacific | Ron Thulin, Dave Lapham |
| 7:30 PM | █ Oregon State @ San Diego State | CBSSN | Andrew Catalon, Aaron Taylor |
| 7:30 PM | █ Troy @ Mississippi State | FSN regional, ESPN3 | Bob Rathbun, Tim Couch |
| 7:45 PM | █ Auburn @ #6 LSU | ESPN | Brad Nessler, Todd Blackledge |
| 8:00 PM | █ Kansas State @ Texas | ABC | Brent Musburger, Kirk Herbstreit |
| 8:00 PM | █ #15 Michigan @ Connecticut | ABC | Sean McDonough, Chris Spielman |
| 8:00 PM | █ Missouri @ Indiana | BTN | Eric Collins, Derek Rackley |
| 8:00 PM | █ UTSA @ UTEP | FCS Atlantic | Brendan Burke, Ben Leber |
| 8:05 PM | █ Hawaii @ Nevada | Time Warner Hawaii, MWC Digital | Robert Kekaula, Dick Tomey |
| 10:00 PM | █ Western Illinois @ UNLV | | |
| 10:15 PM | █ Utah @ BYU | ESPN2 | Mark Jones, Brock Huard |
| 10:15 PM | █ Wyoming @ Air Force | ESPNU | Joe Davis, Dan Hawkins |
| 10:30 PM | █ New Mexico State @ #13 UCLA | Pac-12 Network | Ted Robinson, Glenn Parker |
| 10:30 PM | █ Idaho @ Washington State | Pac-12 Washington | Roxy Bernstein, Anthony Herron |
