| 12:00 PM | 6 Michigan @ Penn State | ABC | Sean McDonough, Todd Blackledge |
| 12:00 PM | 8 Oklahoma @ 13 Baylor | FOX | Gus Johnson, Joel Klatt |
| 12:00 PM | Mississippi State @ 17 Auburn | ESPN | Bob Wischusen, Jordan Rodgers |
| 12:00 PM | Northwestern @ 18 Wisconsin | ESPN2 | Clay Matvick, Rocky Boiman |
| 12:00 PM | West Virginia @ Kansas State | FS1 | Eric Collins, Petros Papadakis |
| 12:00 PM | Central Florida @ Southern Methodist | ESPNU | John Schriffen, Rene Ingoglia |
| 12:00 PM | New Mexico State @ 2 Alabama | SECN | Taylor Zarzour, Matt Stinchcomb |
| 12:00 PM | Samford @ Florida | ESPN+, SECN+ | Mike Couzens, Dustin Fox |
| 12:00 PM | Rutgers @ Indiana | BTN | Cory Provus, Matt Millen |
| 12:00 PM | Connecticut @ Clemson | ACCN | Wes Durham, Roddy Jones |
| 12:00 PM | Bucknell @ Army | CBSSN | Jason Horowitz, Ross Tucker |
| 12:00 PM | Syracuse @ Louisville | ACC RSNs | Evan Lepler, Brian Jordan |
| 12:00 PM | Maine @ Massachusetts | NESN+, FloSports | |
| 12:00 PM | East Carolina @ Memphis | ESPN+ | Richard Cross, Brandon Weeden |
| 12:00 PM | Houston @ Temple | ESPN+ | Courtney Lyle, Leger Douzable |
| 2:00 PM | Utah @ Arizona | P12N | Roxy Bernstein, Lincoln Kennedy |
| 2:00 PM | Georgia State @ Coastal Carolina | ESPN+ | |
| 2:00 PM | Western Kentucky @ Rice | ESPN+ | |
| 2:30 PM | South Alabama @ Appalachian State | ESPN+ | |
| 3:00 PM | Georgia Southern @ Texas State | ESPN+ | |
| 3:30 PM | 19 Purdue @ 4 Ohio State | ABC | Joe Tessitore, Greg McElroy |
| 3:30 PM | 1 Georgia @ Tennessee | CBS | Brad Nessler, Gary Danielson |
| 3:30 PM | Miami @ Florida State | ESPN | Mark Jones, Robert Griffin III, Quint Kessenich |
| 3:30 PM | Iowa State @ Texas Tech | ESPN2 | Beth Mowins, Kirk Morrison |
| 3:30 PM | USC @ California | POSTPONED | |
| 3:30 PM | Minnesota @ 20 Iowa | BTN | Brandon Gaudin, James Laurinaitis |
| 3:30 PM | Duke @ Virginia Tech | ACCN | Chris Cotter, Mark Herzlich |
| 3:30 PM | UAB @ Marshall | CBSSN | John Sadak, Randy Cross |
| 3:30 PM | Boston College @ Georgia Tech | ACC RSNs | Tom Werme, James Bates |
| 3:30 PM | Charlotte @ Louisiana Tech | Stadium | |
| 3:30 PM | Louisiana @ Troy | ESPN+ | |
| 3:30 PM | Florida Atlantic @ Old Dominion | ESPN+ | |
| 3:30 PM | Southern Mississippi @ 23 UTSA | ESPN+ | |
| 3:30 PM | Florida International @ Middle Tennessee | ESPN3 | |
| 4:00 PM | Maryland @ 7 Michigan State | FOX | Joe Davis, Brock Huard |
| 4:00 PM | Tulsa @ Tulane | ESPNU | Kevin Brown, Hutson Mason |
| 4:00 PM | South Carolina @ Missouri | SECN | Dave Neal, Deuce McAllister |
| 4:00 PM | Hawaii @ UNLV | Hawaii PPV,
Team1Sports | |
| 4:00 PM | UTEP @ North Texas | ESPN+ | |
| 5:00 PM | Arkansas State @ ULM | ESPN+ | |
| 5:30 PM | Stanford @ Oregon State | P12N | JB Long, Max Browne |
| 7:00 PM | 11 Texas A&M @ 15 Ole Miss | ESPN | Chris Fowler, Kirk Herbstreit |
| 7:00 PM | Kentucky @ Vanderbilt | ESPN2 | Anish Shroff, Mike Golic Jr. |
| 7:00 PM | Arizona State @ Washington | FS1 | Dan Hellie, Petros Papadakis |
| 7:00 PM | Air Force @ Colorado State | CBSSN | Dave Ryan, Aaron Murray |
| 7:00 PM | New Mexico @ Fresno State | Stadium,
KFRE CW59 Fresno | |
| 7:30 PM | 9 Notre Dame @ Virginia | ABC | Dave Pasch, Dusty Dvoracek, Tom Luginbill |
| 7:30 PM | TCU @ 10 Oklahoma State | FOX | Tim Brando, Spencer Tillman |
| 7:30 PM | Kansas @ Texas | ESPNU | Roy Philpott, Kelly Stouffer |
| 7:30 PM | 25 Arkansas @ LSU | SECN | Tom Hart, Cole Cubelic |
| 7:30 PM | 16 N.C. State @ 12 Wake Forest | ACCN | Dave O'Brien, Tim Hasselbeck |
| 9:00 PM | Colorado @ UCLA | P12N | Ted Robinson, Yogi Roth |
| 10:30 PM | Washington State @ 3 Oregon | ESPN | Dave Flemming, Rod Gilmore |
| 10:30 PM | Utah State @ San Jose State | FS1 | Jeff Levering, Robert Smith |
| 10:30 PM | Nevada @ 22 San Diego State
(in Carson) | CBSSN | Rich Waltz, Aaron Taylor |
