| 12:00 PM | 1 Clemson @ Georgia Tech | ABC | Bob Wischusen, Dan Orlovsky |
| 12:00 PM | Kansas @ West Virginia | FOX | Gus Johnson, Joel Klatt |
| 12:00 PM | 15 Auburn @ South Carolina | ESPN | Dave Pasch, Greg McElroy |
| 12:00 PM | Navy @ East Carolina | ESPN2 | Lincoln Rose, Keith Moreland |
| 12:00 PM | 8 Cincinnati @ Tulsa | POSTPONED | |
| 12:00 PM | Texas State @ South Alabama | ESPNU | Clay Matvick, Rocky Boiman |
| 12:00 PM | Kentucky @ 18 Tennessee | SECN | Tom Hart, Jordan Rodgers, Cole Cubelic |
| 12:00 PM | Pittsburgh @ 13 Miami | ACCN | Chris Cotter, Mark Herzlich |
| 12:00 PM | Liberty @ Syracuse | ACC RSNs | Evan Lepler, Charles Arbuckle |
| 12:00 PM | South Florida @ Temple | ESPN+ | Dave Leno, Ken Dunek |
| 1:30 PM | Army @ UTSA | CBSSN | Dave Ryan, Corey Chavous |
| 1:30 PM | Western Kentucky @ UAB | Stadium RSNs | Chris Hassel, A.J. Hawk |
| 2:30 PM | Louisville @ 4 Notre Dame | NBC | Mike Tirico, Tony Dungy |
| 3:30 PM | UCF @ Memphis | ABC | Mark Jones, Roddy Jones |
| 3:30 PM | Ole Miss @ Arkansas | SECN | Dave Flemming, Rod Gilmore |
| 3:30 PM | Duke @ N.C. State | ACC RSNs | Tom Werme, James Bates |
| 3:30 PM | Eastern Kentucky @ Troy | ESPN3 | |
| 4:00 PM | UMass @ Georgia Southern | ESPN2 | Bill Roth, Dustin Fox |
| 4:00 PM | 11 Texas A&M @ Mississippi State | ESPN | Dave Neal, DJ Shockley |
| 4:00 PM | Virginia @ Wake Forest | ACCN | Wes Durham, Eric Wood |
| 5:00 PM | North Texas @ Middle Tennessee | Stadium RSNs | Chris Vosters, Max Stark |
| 6:00 PM | Marshall @ Louisiana Tech | CBSSN | Rich Waltz, Aaron Murray |
| 7:30 PM | 5 North Carolina @ Florida State | ABC | Sean McDonough, Todd Blackledge, Todd McShay |
| 7:30 PM | Southern Mississippi @ UTEP | ESPN2 | Roy Philpott, Kelly Stouffer |
| 8:00 PM | 3 Georgia @ 2 Alabama | CBS | Brad Nessler, Gary Danielson |
| 8:00 PM | Florida International @ Charlotte | ESPNU | Mike Couzens, Rene Ingoglia |
| 8:00 PM | Boston College @ 23 Virginia Tech | ACCN | Dave O'Brien, Tim Hasselbeck |
